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March 5, 2025
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Answer Summary

Members overwhelmingly shared positive experiences with Opsumit for pulmonary arterial hypertension, with many reporting no noticeable side... Read more

Members overwhelmingly shared positive experiences with Opsumit for pulmonary arterial hypertension, with many reporting no noticeable side effects, improved walking ability, increased activities, and stabilized or reduced pulmonary pressures over periods ranging from one to eight years. Several members noted they take Opsumit in combination with other medications like Adempas, Tadalafil, or Uptravi, with one member reporting a dramatic pressure drop from 77 to 31 after switching to Winrevair, while another had to stop due to blood in their urine. A recurring theme was cautious optimism, with members acknowledging that while the medication has helped many stay stable or improve, some pressures continue to rise, and the journey requires ongoing monitoring and adjustments.

A myPHteam Member

I am and have had success, my pressure dropping by almost 20pts…
Good luck with it

March 9, 2025
A myPHteam Member

Hi Sharon. I've been on Opsumit since September of 2022 and I haven't had any problems with it. I also take Adempas. I have moderate IPAH with PAP of 48 and I have remained stable with 6-month follow-ups.

March 9, 2025
A myPHteam Member

After I was diagnosed I went on Adempas and Tyvaso dpi. My pressure increased from 48 to 77 during that time - 1 yr. I recently, 6mos now have been on Winrevair and stopped Tyvaso. Monday echo says pressure now 31. Miracle drug. Get on it if you can.

March 6, 2025
A myPHteam Member

I also have PAH and am on Opsumit and sidentifil and furisimide. I haven’t haven’t had any trouble with it, but my pressures continue to go up, but then maybe they would be worse without it. Hope it works well for you!!

March 5, 2025
A myPHteam Member

I was diagnosed with PAH about a year ago. I am on a combination treatment of Opsumit and Tadalafil. I have had no issues with Opsumit. I now walk longer and have increased my activities.

March 5, 2025

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