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A myPHteam Member asked a question 💭
Cyprus

I am taking sildenafil which addresses the Nitric Oxide pathway. Someone told me that I should not be administered pain relief gases such as Entonox because the two combined could result in a sharp drop in blood pressure. Is this true? Would it be wise to have a medical alert bracelet (or similar) to ensure that this does not happen in any emergency situation?????

September 20, 2024
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A myPHteam Member

Thanks for that. I am thinking of having a medical bracelet done stating that I have PAH and am on Sildenafil!

September 30, 2024
A myPHteam Member

Maybe if we suffered from regular high blood pressure then I would be concerned. I try to remember that a lot of medical professionals are not familiar with the condition that I am diagnosed with. I do believe that our diagnoses by doctor or specialist would mention any concerns.

September 30, 2024
A myPHteam Member

Hi Ann, I had a special cardiac ct scan last week & was questioned if I was taking Viagra. During the scan, they administer Nitroglycerine - and I was told that Nitroglycerine & Soldenafil - the two combined could result in a sharp drop in blood pressure. The nurse cautioned me to tell my family. If ambulance was ever called for emergency due to heart issue, they would need to know that I am taking Soldenafil. (This is the first I heard about this --- but I did not read all the drug paperwork like I should have.)

September 21, 2024
myPHteam

While the provided context does not specifically mention the interaction between sildenafil and pain relief gases like Entonox, it does highlight some important considerations:

1. Sildenafil and Heart Risks
- Sildenafil (Viagra) has been shown to potentially worsen clinical outcomes in patients with certain heart Show Full Answer

While the provided context does not specifically mention the interaction between sildenafil and pain relief gases like Entonox, it does highlight some important considerations:

1. Sildenafil and Heart Risks:
- Sildenafil (Viagra) has been shown to potentially worsen clinical outcomes in patients with certain heart conditions, such as valvular heart disease, by raising heart risks (source: "Viagra Won't Help, and May Harm, Patients With a Heart Valve Disorder").

2. Nitric Oxide Pathway:
- Sildenafil works by blocking the enzyme phosphodiesterase-5 (PDE-5), which increases the effect of nitric oxide, helping to relax blood vessels and improve blood flow (source: "How Do Pulmonary Arterial Hypertension Medicines Work").

3. Monitoring and Safety:
- Given the potential for interactions and the importance of managing blood pressure in pulmonary hypertension, it is crucial to be cautious with any additional medications or treatments that could affect blood pressure.

4. Medical Alert Bracelet:
- Wearing a medical alert bracelet can be a wise precaution. It ensures that healthcare providers are aware of your condition and current medications, which is particularly important in emergency situations.

In summary, while the specific interaction between sildenafil and Entonox is not detailed in the provided context, it is advisable to discuss this with your healthcare provider. They can provide personalized advice and determine whether a medical alert bracelet is appropriate for your situation.

September 20, 2024

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