I guess that is possible. I got my diagnosis when I was not overweight. Just working a lot. It was when I couldn't breathe and sat around all the time that I got over weight. The working all the time and not being able to take a potty break is what caused my kidney problems. So far I have heard a few different causes. I have been told if I didn't smoke I wouldn't have this problem. I have NEVER smoked a day in my life. My mom did. In 2002 I believe I was the first in this area diagnosised with PAH. They gave me Revatio and I had the pleasure of educating every Pharmacy I went to fill my prescription why I a female would want a man's ED drug? I had to go inside the store and meet with the main person and explain. It was quite an experience and after awhile I started just laughing with them because there were no males in my life because they called my Doctor to ask why it was ordered. HA! HA! They didn't believe me. Life is such fun at times. HA! HA!