PHOSPHODIESTERASE-5 (PDE-5) INHIBITOR
Revatio is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to improve exercise and delay disease progression in cases of pulmonary arterial hypertension. Revatio may be referred to by its drug name, sildenafil. Sildenafil is also sold to treat erectile dysfunction under the brand name Viagra.
Revatio is a phosphodiesterase-5 (PDE-5) inhibitor. Revatio inhibits the action of an enzyme called phosphodiesterase-5 (PDE-5), which works to control blood flow. In cases of pulmonary hypertension, Revatio is believed to work by dilating the pulmonary arteries.
How do I take it?
Prescribing information states that Revatio is taken three times a day orally or by intravenous injection.
Revatio comes in tablet, oral suspension, and single-use vial forms.
The FDA-approved label for Revatio lists common side effects including headache, insomnia, flushed skin, cold symptoms, stomach upset, nosebleeds, and dyspnea (difficulty breathing).
Rare but serious side effects listed for Revatio include hypotension (low blood pressure) and vision or hearing problems.
For more details about this treatment, visit:
Revatio — Pfizer
Phosphodiesterase 5 inhibitors — Pulmonary Hypertension Association UK