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Opsynvi is a combination medication that contains macitentan (an ERA) and tadalafil (a PDE inhibitor) used to treat PAH. The most common side effects include:

• Headaches
• Nausea and bloating
• Vomiting
• Diarrhea
• Light-headedness
• Flushing (feeling of warmth)
• Upper respiratory congestion
• Skin rash Additional side Show Full Answer

Opsynvi is a combination medication that contains macitentan (an ERA) and tadalafil (a PDE inhibitor) used to treat PAH. The most common side effects include:

• Headaches
• Nausea and bloating
• Vomiting
• Diarrhea
• Light-headedness
• Flushing (feeling of warmth)
• Upper respiratory congestion
• Skin rash Additional side effects that may occur include:

• Fever
• Coughing
• Respiratory tract infections
• Sinus infections
• Urinary tract infections
• Edema (fluid buildup causing swelling in arms/legs)
• Unusual weight changes
• Reduced urination

If you experience any side effects that interfere with daily activities, contact your healthcare provider. They can adjust your dosage or modify your treatment plan to better manage your PAH while minimizing side effects.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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