Answer Summary

Members shared their experiences with Letaris (ambrisentan) for pulmonary hypertension, with many reporting that persistent nasal congestion... Read more

Members shared their experiences with Letaris (ambrisentan) for pulmonary hypertension, with many reporting that persistent nasal congestion and stuffiness is a very common side effect, though the medication has been effective for some members for years, even up to a decade. Several members offered practical relief strategies including saline nasal sprays (especially Arm & Hammer Nighttime with Eucalyptus), Flonase, and Breathe Right nasal strips, with one member proudly wearing the strips in public because breathing comfortably matters more than appearance. A recurring theme was learning to accept the annoying sinus issues as an unavoidable trade-off when the medication is working well to manage pulmonary pressures, though one member had to stop due to severe abdominal pain, reminding others that side effects can vary widely.