I was put on Spironalactone 25mg. while taking Valsartin HCTZ. My blood pressure would drop on top down into the 90s. The bottom number pretty well stayed normal. I find it hard to function when the top number is that low. We have taken away the HCTZ part of the Valsartin. That has helped some,but where my ankles had no swelling, now there is a little puffiness. Struggling with fatigue is my biggest problem.